📖 COVID-19 in pregnancy: implications for fetal brain development

Shook et al / Trends in Molecular Medicine • 13 February 2022

SARS-CoV-2 infection in pregnancy is known to confer a risk of increased morbidity and mortality for the mother.


Placental and fetal infection with SARS-CoV-2 have been rare to date; SARS-CoV-2 infection in pregnancy appears most likely to impact fetal brain development via maternal and placental immune activation.


Maternal and placental immune activation may impact the placenta and developing fetal brain via induction of immune activation and proinflammatory cytokine production, dysregulation of serotonin/other neurotransmitter signaling, and increased oxidative stress.



📖 (13 Feb 2022 ~ Trends in Molecular Medicine) COVID-19 in pregnancy: implications for fetal brain development ➤


© 2022 Shook et al / Trends in Molecular Medicine.