📖 Human Endogenous Retrovirus, SARS-CoV-2, and HIV Promote PAH via Inflammation and Growth Stimulation

Wang et al / International Journal of Molecular Sciences • 18 April 2023

‘Pulmonary arterial hypertension (PAH) is a pulmonary vascular disease characterized by the progressive elevation of pulmonary arterial pressures.’


Pulmonary Arterial Hypertension (PAH) is a progressive lung disease that affects the heart and lungs.


It is caused when the tiny arteries in the lungs become thickened and narrowed, causing abnormally high blood pressure in the pulmonary artery.


Symptoms include shortness of breath during exercise, fainting spells, dizziness, swelling of the ankles or legs, chest pain, and a racing pulse.


‘It is becoming increasingly apparent that inflammation contributes to the pathogenesis and progression of PAH.


Several viruses are known to cause pulmonary arterial hypertension (PAH), such as SARS-CoV-2, Human Endogenous Retrovirus K (HERV-K), and Human Immunodeficiency Virus (HIV), in part due to acute and chronic inflammation.’



📖 (18 Apr 2023 ~ International Journal of Molecular Sciences) Human Endogenous Retrovirus, SARS-CoV-2, and HIV Promote PAH via Inflammation and Growth Stimulation ➤


© 2023 International Journal of Molecular Sciences.