‘All subtypes of dementia, irrespective of patients’ previous dementia types, behaved like rapidly progressive dementia following COVID-19 [infection with SARS-CoV-2].’

❦ ‘All subtypes of dementia, irrespective of patients’ previous dementia types, behaved like  rapidly progressive dementia following COVID-19 [infection with SARS-CoV-2], according to new research in the Journal of Alzheimer’s Disease Reports.

In addition to this, the team of investigators found that the line of demarcation between different types of dementia became remarkably blurry post-COVID-19.

Researchers found that the characteristics of a particular type of dementia changed following COVID-19, and both degenerative and vascular dementias started behaving like mixed dementia both clinically and radiologically.

A rapidly and aggressively deteriorating course was observed in patients having insidious onset, slowly progressive dementia, and who were previously cognitively stable.

Cortical atrophy was also evident in the study’s subsequent follow-ups.

Coagulopathy involving small vessels and inflammation, which were further correlated with white matter intensity changes in the brain, was considered the most important pathogenetic indicator.

The rapid progression of dementia, the addition of further impairments / deterioration of cognitive abilities, and the increase or new appearance of white matter lesions, suggest that previously compromised brains have little defense to withstand a new insult (i.e. a ‘second-hit’-like [SARS-CoV-2] infection).’

‘Cognitive postscripts of COVID-19... characterized by multi-domain cognitive impairments, are now being reckoned as the most devastating sequelae of COVID-19.’

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📖 (4 Apr 2023 ~ IOS Press / EurekAlert) New study shows SARS-CoV-2 infection accelerates the progression of dementia ➤

📖 (14 Feb 2023 ~ Dubey et al / Journal of Alzheimer’s Disease Reports) The Effects of SARS-CoV-2 Infection on the Cognitive Functioning of Patients with Pre-Existing Dementia ➤

© 2023 IOS Press / Journal of Alzheimer’s Disease Reports.

❦ Alzheimer’s & Dementia: Elsewhere on C19.Life...

➲ (2022) Risk for Developing Alzheimer’s Disease Increases by 50-80% In Older Adults Who Caught COVID-19 ➤

‘Older people who were infected with COVID-19 show a substantially higher risk – as much as 50% to 80% higher than a control group – of developing Alzheimer’s disease within a year.

People 65 and older who contracted COVID-19 were more prone to developing Alzheimer’s disease in the year following their COVID diagnosis.

And the highest risk was observed in women at least 85 years old.’

➲ (2021) The Impact of the COVID-19 Pandemic on Dementia Risk: Potential Pathways to Cognitive Decline ➤

‘SARS-CoV-2 infection initiates a disease progression that has the potential to promote cognitive decline and exacerbate pre-existing dementia.’

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© 2024 AI Art: C19.Life.